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Image Search Results
Journal: EBioMedicine
Article Title: Inhibition of Nwd1 activity attenuates neuronal hyperexcitability and GluN2B phosphorylation in the hippocampus
doi: 10.1016/j.ebiom.2019.08.050
Figure Lengend Snippet: Nwd1 location in excitatory synapses acute seizures brain tissues. (a–b) Immunofluorescence staining for Nwd1 in the cerebral cortex of individuals with TLE patients. Nwd1 co-localizes with excitatory synapses marker postsynaptic density protein PSD95 but presynaptic vesicular marker Vglut1 (a) and less in inhibitory synapses marker GAD67 (b). (c–d) Immunofluorescence of Nwd1 in the hippocampi from KA-induced acute seizures mice show that Nwd1 colocalizes with PSD95 and lacks of colocalization of Nwd1with Vglut1 (c) and less in GAD67 (d) in the neuronal cells.
Article Snippet: The following primary antibodies were used in this study: a rabbit anti-NWD1 pAb (1:500, Proteintech Group, Inc., Cat# 25025–1-AP); a rabbit anti-GAPDH mAb (1:1000, Proteintech Group, Inc., Cat# 10494–1-AP); a guinea pig anti-MAP2 mAb (1:300, Synaptic Systems, Cat# 188004); a mouse anti-GFAP mAb (1:200, Proteintech Group, Inc., Cat# 60190–1-Ig); a
Techniques: Immunofluorescence, Staining, Marker
Journal: Cell
Article Title: Targeting peripheral somatosensory neurons to improve tactile-related phenotypes in ASD models
doi: 10.1016/j.cell.2019.07.024
Figure Lengend Snippet: KEY RESOURCES TABLE
Article Snippet: Mouse anti GAD67 ,
Techniques: Virus, Recombinant, Patch Clamp, Cloning, Software